The long-awaited showdown between Kayla Harrison and Amanda Nunes is finally set to materialize. Harrison puts her UFC women’s bantamweight title on the line against the former two-division champion Nunes in the co-main event of UFC 334, scheduled for this Saturday, November 14, at Madison Square Garden in New York City. Here is everything you need to know about the championship clash, including the latest betting lines, followed by our official pick and prediction.

Date: Saturday, November 14, 2026

Preliminary Card: 7:00 p.m. ET

Early Prelims: 5:00 p.m. ET

UFC 334 Fight Card: Location & Broadcasting

Location: Madison Square Garden, New York City

How to Watch or Stream:

  • Main Card: CBS, Paramount+
  • Preliminary Card: Paramount+
  • Early Prelims: Paramount+, UFC Fight Pass

UFC 334 Full Fight Lineup

Main Card: Ciryl Gane vs. Josh Hokit, Kayla Harrison vs. Amanda Nunes, Caio Borralho vs. Yousri Belgaroui, Uroš Medić vs. Kevin Holland, Bilal Hasan vs. Luis Gurule

Preliminary Card: Stephen Thompson vs. Charles Radtke, Drew Dober vs. Chris Duncan, Jim Miller vs. Terrance McKinney, Donte Johnson vs. César Almeida

UFC 334 Early Preliminary Card

Jared Gordon vs. Melquizael Costa, Macy Chiasson vs. Bia Mesquita, Alatengheili vs. Juan Díaz, Evan Elder vs. Samuel Sanches

Betting Odds and Market Movement

When betting opened for this women’s bantamweight championship bout, Harrison initially stood as a -300 favorite against Nunes at +247. Those figures have since tightened significantly. Currently, Harrison is positioned at -171, while Nunes sits at +151.

When the bout was initially booked for UFC 324, Harrison opened at -170 with Nunes at +145. The reigning titleholder quickly gained momentum, shifting to -190 while the former queen drew a +165 return.

Fighter Profile: Kayla Harrison

A two-time Olympic gold medalist in judo (2012 and 2016), Kayla Harrison boasts a professional record of 19-1. She launched her MMA career in 2018 within the PFL 155-pound division, tearing through her initial six opponents with three submissions, two knockouts, and a decision before capturing the lightweight crown by defeating Larissa Pacheco via decision.

In November 2020, Harrison secured a TKO victory over Courtney King in a 145-pound affair before returning to lightweight. She claimed the 2021 PFL tournament title with a submission win over Taylor Guardado.

By 2022, Harrison maintained an unblemished 15-0 record, which came to an end in the PFL lightweight tournament finals when Pacheco earned a unanimous decision. Harrison fought once more under the PFL banner, outpointing former UFC athlete Aspen Ladd via decision in a 150-pound catchweight bout in November 2023.

In January 2024, the UFC announced her signing into the 135-pound weight class. Harrison made an immediate statement at UFC 400, submitting former bantamweight titleholder Holly Holm in the second round. She followed this up with a unanimous decision victory over Ketlen Vieira.

In June 2025, Harrison secured the UFC women’s bantamweight championship by forcing Julianna Peña to submit in the second round at UFC 316. That victory prompted Nunes to step out of retirement, setting the stage for their historic collision at UFC 334.

Fighter Profile: Amanda Nunes

If Amanda Nunes is not universally crowned the greatest female mixed martial artist in history, she is undoubtedly at the heart of the discussion. Debuting in the UFC in 2013 with a 7-3 record, she rattled off two consecutive first-round knockouts before suffering a third-round TKO loss to Cat Zingano in her third promotional appearance.

Nunes would not taste defeat again until December 2021. During a legendary 12-fight winning streak, she captured the bantamweight championship and successfully defended it five times, recording first-round stoppages against icons such as Miesha Tate, Ronda Rousey, and Holly Holm. Nunes also claimed the featherweight belt, defending it twice, most notably seizing the 145-pound throne with a first-round demolition of Cris Cyborg, who had remained undefeated for over 13 years.

In a sluggish and puzzling performance in December 2021, Nunes surrendered her 135-pound strap to Julianna Peña via second-round submission. She reclaimed the bantamweight gold in July 2022 with a decision win over Peña, and subsequently defended the title against Irene Aldana in July 2023. Following that defense, she walked away from active competition as the dual-division champion.

“Double champion forever,” Nunes declared post-fight. “This is the perfect night to retire.”

Their original UFC 324 meeting was delayed in mid-January after Harrison underwent successful surgery to repair herniated discs in her neck. On fight night, Nunes will be 38 years old, while Harrison will be 36.

Pick and Prediction

The primary X-factors heading into this co-main event are Harrison’s surgically repaired neck versus the ring rust of Nunes. Expect Harrison to leverage her superior strength and suffocating top control to grind out a hard-fought decision win over the former double champ. Additionally, there is strong betting value to consider regarding a potential Harrison submission.